Carluke railway station is a railway station on the West Coast Main Line (WCML) that serves the town of Carluke, South Lanarkshire, Scotland. The station is managed by ScotRail and is predominantly served by Argyle Line commuter trains running between Lanark and Glasgow Central.

The station lies at the western edge of the town, and enjoys panoramic views of the Clyde Valley and beyond to the hills of Lanarkshire and Ayrshire.